The authors' conclusion emphasized the close relationship between H pylori and gastric cancer. The authors indicate that H pylori may make initiated cells of gastric cancer escape from the control of the neighboring ones by inhibiting GJIC. Consequently, H pylori, especially CagA+ strains, play an important role in the developmental process of gastric cancer.
The results of this article provide an innovative direction to develop new drugs for curing gastric cancer. That means drugs able to restore GJIC in cells with deficient gap junction may be used in the prevention and/or treatment of human gastric cancer.
Source-Eurekalert
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