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Risk of Oropharyngeal Cancer Increased by HPV Infection

by VR Sreeraman on  August 27, 2007 at 2:35 PM Cancer News   - G J E 4
Risk of Oropharyngeal Cancer Increased by HPV Infection
A review conducted at The University of Texas M. D. Anderson Cancer Center in Houston suggests that high rates of oropharyngeal cancers, particularly cancers of the tonsil and base of tongue, may be due to oncogenic human papillomavirus (HPV) infection.
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While the overall incidence of head and neck cancers has fallen in the United States, the rate of oropharyngeal cancers is stagnant.

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Dr. Erich M. Sturgis and Dr. Paul Cinciripini say that the stagnate incidence rates of oropharyngeal cancers, particularly among men under 45 years old, may be due to the rising prevalence of oropharyngeal exposure to an oncogenic virus.

According to them, the literature points to exposure to HPV - especially strain 16 - as having the strongest association to oropharyngeal cancers.

The authors, however, suggest that a recently approved HPV vaccine may ultimately have a significant impact on the incidence of oropharyngeal tumours.

"While the cervical cancer and dysplasia prevention policy of HPV16/18 vaccination of young women and adolescent females are commended, we fear that vaccination programs limited to females will only delay the potential benefit in prevention of HPV16/18 associated oropharyngeal cancers, which typically occur in men," the authors say.

"Encourage the rapid study of the efficacy and safety of these vaccines in males and, if successful, the recommendation of vaccination of young adult and adolescent males," they conclude.

The review has been published in Cancer, a peer-reviewed journal of the American Cancer Society.

Source: ANI
LIN/J
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i had genital wart in 98, facial wart in 2001. treated with cautery . How do i know the strain of virus ? or the risk of developing oral cancer?
guest Tuesday, November 13, 2007
There are things those that are not vaccinated against HPV can do to lower their risk of oral cancer. Currently HPV is felt to be responsible for roughly 25 percent of oral cancers in the US. A study published in the journal "Cancer", showed that a diet high in foods containing lutein, vitamin A, vitamin C and papaya accelerated clearance of the HPV virus, leaving less time for it to cause the inflammation that can lead to cancer. Though recommendations for screening are not available, it would seem wise that individuals see their dentists regularly. Many dentists now routinely screen for oral cancer. Lynne Eldridge MD Author, "Avoiding Cancer One Day At A Time" http://www.avoidcancernow.com
guest Monday, August 27, 2007

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