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Resistance to Malaria Drug Spreads in Asia: WHO

by VR Sreeraman on  November 19, 2010 at 3:03 PM Drug News   - G J E 4
The World Health Organisation warned Thursday that resistance to malaria drug artemisinin appeared to be spreading in the region from the Cambodia-Thailand border, where it was first detected.
 Resistance to Malaria Drug Spreads in Asia: WHO
Resistance to Malaria Drug Spreads in Asia: WHO
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"There is some early evidence that resistance to artemisinins may also be emerging on the Myanmar-Thailand border," said the WHO in a statement.

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"There is also concern that resistance could spread from the Cambodia-Thailand border to Africa, as it did with anti-malaria drugs such as chloroquine and sulfadoxine-pyrimethamine in the 1960s and 1970s," it added.

Pascal Ringwald, who co-authored a WHO study into the issue, said the WHO is undertaking "complementary studies to confirm that it is indeed drug resistance. That should take a year."

In February 2009, anti-malarial drug resistance was confirmed by the WHO at the Cambodia-Thailand border.

But the latest WHO study found that some 10-20 percent of patients at the Myanmar-Thailand border continued to show signs of malarial parasites in the blood after a three-day treatment with artemisinin combination therapy.

Likewise, at the China-Myanmar border, studies show that a quarter of patients who took oral artesunate monotherapy remained parasitaemic on the third day of treatment.

Similar signs were observed in a a province in Vietnam.

The WHO called for "careful monitoring" on the issue, and said that only 34 percent of malaria-endemic countries are complying with recommendations to monitor the efficacy anti-malarial drugs.

Half of the world's population is exposed to malaria which kills 860,000 people every year, according to the WHO.

Source: AFP
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