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Researchers Reverse Mental Retardation Symptoms in Mice
"These behavioural abnormalities are ameliorated, partially or fully, by inhibiting the enzymatic activity of PAK,” Tonegawa said.
"Strikingly, PAK inhibition also restored electrical communication between neurons in the brains of the FXS mice, correcting their behavioural abnormalities in the process," he added.
"Our study suggests that inhibiting a certain enzyme in the brain could be an effective therapy for countering the debilitating symptoms of FXS in children, and possibly in autistic kids as well," Hayashi said.
The findings of the study will be published in the online early edition of the Proceedings of the National Academy of Sciences
Source-ANI
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