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Researchers Discover Potential New One-dose Malaria Drug

by VR Sreeraman on September 03, 2010 at 12:03 PM Drug News

Researchers have discovered a promising new malaria drug with the potential to treat resistant strains of the deadly disease in a single dose, according to a study published Thursday in the journal Science.

Researchers Discover Potential New One-dose Malaria Drug

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The drug could be ready for clinical trials as soon as later this year and appears to be more potent than currently used drugs, researchers said.

"We're very excited by the new compound," said study author Elizabeth Winzeler, a professor at the Scripps Research Institute and member of the Genomics Institute of the Novartis Research Foundation.

"It has a lot of encouraging features as a drug candidate, including an attractive safety profile and potential treatment in a single oral dose."

Current treatment methods require patients to take drugs between one and four times daily for three to seven days. Reducing the treatment to a single dose leaves less opportunity for the parasites to develop a resistance to the drug, researchers said.

There were approximately 247 million cases of malaria in 2008 which caused nearly one million deaths, mostly among young children in Africa, according to the World Health Organization.

Malaria is contracted when people are bitten by mosquitoes infected with a parasite called Plasmodium.

It causes fever and vomiting and can quickly become life-threatening by disrupting the blood supply to vital organs.

The parasites have developed resistance to a number of malaria medications in many parts of the world and it has been more than a decade since a new class of malaria drugs began to be widely used.

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Researchers Discover Potential New One-dose Malaria Drug

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