Research Uncovers Genetic Link Between Emphysema and Lung Cancer

by VR Sreeraman on  June 11, 2011 at 4:07 PM Respiratory Disease News
RSS Email Print This Page Comment bookmark
Font : A-A+

Researchers have found that a gene which causes emphysema may also contribute to the development of lung cancer.
 Research Uncovers Genetic Link Between Emphysema and Lung Cancer
Research Uncovers Genetic Link Between Emphysema and Lung Cancer

In a study by UT Southwestern Medical Center researchers, mice bred to have the human gene pleiomorphic adenoma gene-like 2 (PLAGL2) all developed emphysema, and by gender also developed lung cancer at rates as high as one in every six rodents.

Although the new study showed PLAGL2 as a contributing factor in emphysema and lung cancer development, the diseases form in opposite ways. Emphysema arises from cell death or injury, while lung cancer involves uncontrolled cell growth.

"We think this gene induces emphysema by causing stem cells in the lung to die," said Dr. Jonathan Weissler, vice chairman of the department of medicine and chief of medicine at UT Southwestern University Hospital and senior author of the study.

"The cells that don't die through apoptosis would be more likely to have uncontrolled growth" and become cancerous, suggesting a genetic link between the diseases.

The study will be published in the journal Lung Cancer.

Source: ANI

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Lung Cancer Cancer and Homeopathy Genetics and Stem Cells Cancer Facts Asbestosis Cancer Tattoos A Body Art Pneumoconiosis Smoking among Women Silicosis 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive

Loading...