Research Analyzes Repeat Surgery for Trigeminal Neuralgia Patients

by Sreeraman on  May 08, 2009 at 12:58 PM Research News
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Trigeminal neuralgia (TN, also known as tic douloureaux) is the most common facial pain syndrome with approximately 15,000 new patients diagnosed each year in the United States. TN is characterized by episodic, intense, shock-like pain in one or more divisions of the trigeminal nerve.

Typically, women are affected more frequently than men, and the pain generally follows a relapsing and recurring course. It is common for patients to be misdiagnosed for many years after the pain begins. The most common cause of TN is considered idiopathic - compression of the trigeminal nerve by a blood vessel as it exits the brainstem, but TN can also occur secondary to tumors or demyelinating disease (multiple sclerosis).

TN usually responds well initially to medical therapy. However, patients with refractory disease or those who cannot tolerate medical therapy are candidates for surgery. An estimated 8,000 patients with TN undergo surgery each year in the United States, at a cost exceeding $100 million. Although TN surgery is successful in about 60 to 90 percent of cases, some patients are especially challenging and continue to have persistent or recurrent TN despite multiple operations.

Researchers at the Mayo Clinic investigated surgical outcome in trigeminal neuralgia patients who experienced multiple failed surgeries for this condition. The results of this study, Surgical Management of Trigeminal Neuralgia Patients Who Have Failed Three or More Prior Operations, will be presented by Bruce E. Pollock, MD, 3:09 to 3:20 pm, Tuesday, May 5, 2009, during the 77th Annual Meeting of the American Association of Neurological Surgeons in San Diego. Kathy J. Stien, RN, is the co-author.

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