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Reduced Growth in Lung Cells in Vitamin A Derivative Based Treatment
October 31, 2007 at 3:53 PM
Drug News
In an accompanying editorial, Eva Szabo, M.D., of the National Cancer Institute in Bethesda, Md., discusses the appropriateness of using the biomarker Ki-67 as an alternative endpoint in cancer prevention trials. While the biomarker showed that the retinoid agents were able to reduce cell growth, she says it is still too soon to test them in more advanced clinical trials. “We do not have a full understanding of the effects of these agents on [lung cells] or their effects during the full spectrum of carcinogenesis,” she writes.
Source-Eurekalert
GAN/C
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