A compound in red wine may ward off many of the signs of ageing, including cardiovascular disease, cataracts and decreased bone density, but does not seem to extend the lifespan, according to a new study on mice.
Researchers from Harvard Medical School and National Institute on Aging found that feeding the rodents resveratrol led to a reduction in inflammation and cataract formation and improved bone mineral density and motor skills.
However, these health improvements came without necessarily extending the animals' lifespan.
David Sinclair and Rafael de Cabos team further show evidence that resveratrol mimics the beneficial effects of eating fewer calories.
In mice, they found that resveratrol induces gene activity patterns in multiple tissues that parallel those induced by dietary restriction and every-other-day feeding.
"From a health point of view, the quality of life of these mice at the end of their days is much better. It suggests that resveratrol may extend productive independent life, rather than just extending life span, said de Cabo of the National Institute on Aging.
" I was most surprised by how broad the effects were in the mice," added David Sinclair of Harvard Medical School.
"Usually, you focus on slowing down or ameliorating one disease at a time. In this case, resveratrol influences a whole series of seemingly unrelated diseases associated with aging."
Sinclair said he expects some of the effect seen in the mice would have even greater impact if they hold in humans. That's because, unlike people, mice usually don't die as a result of heart disease, or suffer from weakening bones.