login
Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
Protein Conferring Protection on Malaria Parasite Identified
They have characterized HDP and demonstrated that it plays a major role in protecting Plasmodium as the pathogen pursues infection of its host.
The Plasmodium parasite, which is responsible for causing malaria in humans is transmitted through the bites of infected mosquitoes. Once inside the human body, the parasite initially develops in the liver and later, upon release, infects red blood cells.
After a host of red blood cells get infected, a rapid growth ensues, supported by the parasite's consumption of hemoglobin, the oxygen-transporting protein that constitutes a massive 90 percent of the total protein present inside each red blood cell.
Destruction on this scale releases large quantities of heme, the prosthetic group responsible for oxygen transport in hemoglobin.
Free heme is highly dangerous and to protect itself from this toxic onslaught, the parasite uses a novel mechanism where it rapidly converts heme into a crystalline material known as hemozoin.
"We discovered HDP as part of a functional genomics initiative that is focused on the identification of malaria proteins involved in disease pathology. A combination of cellular and biochemical approaches allowed us to rigorously characterize HDP," said Dr. Dharmendar Rathore, Assistant Professor at VBI.
|
|
|
More News on: Malaria-water, Tapeworm Infections, Malaria, Mosquito Diseases, Trypanosomiasis, Protein Catabolic Rate, Fever
 Comment & Contribute
|
Medwonders Health Network
- Health News Index
 | Quiz on Malaria Malaria is a common parasitic disease of the tropics, resulting in million deaths every year. Early detection and adequate treatment at the right time can reduce deaths due to malaria. Test your knowledge on this condition by taking this quiz. 
|
- News Quick Links
 |
Malaria
Complete Medindia Resources
|
| News Categories: |
| » | Vivek Oberoi Says There is No Smoking on His Sets |
| » | Gasoigne Swaps Booze for Botox |
| » | Michelle Obama: Name of Olive Tree in Italy |
| » | Beyonce: Most Beautiful Women in the World |
| » | Robin Gibb Recovers from Coma Wakes Up to Cancer |
| More Celebrity News | |
|
