Promising Drug for Type 2 Diabetics

by Medindia Content Team on  January 29, 2008 at 7:56 PM Drug News   - G J E 4
Promising Drug for Type 2 Diabetics
Lead researcher on the study of Anti inflammatory drug salsalate , Allison B. Goldfine, M.D, at Harvard Medical School confirmed that Salsalate has multifarious benefits for a type 2 diabetic. The drug can not only fight the disease by lowering blood glucose and reducing inflammation but may also prevent type 2 diabetes.

Allison said that the drug has a great safety profile, it is inexpensive and has the potential to reduce blood sugar and may prove useful in the prevention of type 2 diabetes.

According to the researchers,  the drug which is similar to aspirin  is promising enough to spur three more trials to see if salsalate can also treat diabetes by lowering blood glucose, slow the progression of coronary artery disease in those with metabolic syndrome, and perhaps prevent diabetes in those at high risk.

Allison said that it has long been known that high doses of aspirin could reduce blood glucose levels, but the risk of stomach bleeding is too high to allow for this treatment to be used.

Allison also noted that it has also been known for several years that inflammatory markers and proteins are elevated in people with diabetes and that aspirin can reduce inflammation.

In animal studies, it has been shown that aspirin could be effective, but since it could not safely be used in humans at high doses, the researchers thought of designing a new drug.

They tried salsalate, a non-steroidal, anti-inflammatory medication that is similar to aspirin but does not cause bleeding in patients at risk for diabetes.

In the double-masked, placebo-controlled study of 20 obese young adults, the researchers found that salsalate substantially reduced blood glucose levels as well as inflammation, and, as a result, may eliminate their risk of developing type 2 diabetes.

Source: ANI

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