The UB regimen is based on the premise that the regulatory system responsible for maintaining cerebral blood flow, which may be dysfunctional in people with a concussion, can be restored to normal by controlled, graded and symptom-free exercise.
The team designed their program in 2004.
Willer said: "We were testing athletes for return to sport using an exercise test...and we decided that if an athlete becomes symptomatic at a heart rate of, say, 140, maybe they could exercise at a heart rate of 125, without complications. We soon discovered that the athletes got better much quicker if they exercised."
To start with physicians in UB's Sports Medicine Concussion Clinic used their approach only with athletes from UB teams, but now they have treated many professional athletes.
John J. Leddy, associate professor of orthopaedics and co-director of UB's Sports Medicine Institute, said: "One of the advantages we offer to professional teams is a more precise test of post-concussion syndrome.
"If the patient does not develop symptoms during the exercise test, then the cause of their difficulties is likely to be another source. Most commonly it is neck strain, which tends to cause headaches that mimic post-concussion headache."
He continued: "The data suggest that some PCS symptoms are related to disturbed cerebral autoregulation, and that after this treatment, the brain was able to regulate blood flow when the blood pressure rose during exercise.
"We think progressive stepwise aerobic training may improve cerebral autoregulation by conditioning the brain to gradually adapt to repetitive mild elevations of systolic blood pressure."
Karl Kozlowski, UB clinical instructor of exercise and nutrition sciences, added: "All of our subjects had been symptomatic for months before treatment and were not getting better on their own...so we are pretty convinced that the regulated exercise program did the trick." A grant application to NIH to conduct such a randomized trial currently is under review.
The findings of the study have appeared in the January issue of the Clinical Journal of Sport Medicine.
Source-ANI
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