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Postmenopausal Women With HIV at Increased Bone Fracture Risk
The study will be published in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM).
"As HIV-infected individuals live longer with potent antiretroviral therapy (ART), metabolic complications such as low bone density and osteoporosis are increasingly recognized," said Michael Yin, MD of Columbia University Medical Center in New York and lead author of the study. "Although numbers of HIV-infected postmenopausal women are increasing and postmenopausal women are at highest risk for osteoporotic fractures, few studies have evaluated skeletal status in this group. We hypothesized that postmenopausal women might be particularly vulnerable to the adverse effects of HIV infection or ART on the skeleton and our results indicate that this may indeed be the case."
To reach the conclusion, Yin and his colleagues initiated a longitudinal study to assess bone health in 92 HIV-positive and 95 HIV-negative postmenopausal women. Bone mineral density of the lumbar spine, femoral neck and hip as well as body composition were measured by dual x-ray absorptiometry (DXA). Researchers found that HIV-positive postmenopausal women had lower bone mineral density at both the spine and hip than HIV-negative postmenopausal women.
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More News on: Oral Health And AIDS, Fracture, Fracture of Knee Cap , AIDS/HIV, Menopause, Infantile Cortical Hyperostosis, AIDS/HIV - Epidemiology, AIDS/HIV - Clinical Features, AIDS/HIV - Health Education, AIDS/HIV - Prevention And Transmission
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