Women with poor quality of life and smoking are almost three times as likely to have premature ovarian failure (POF), finds a new study.
POF not only leads to infertility but also significantly increased morbidity and mortality, as well as a decreased quality of life equivalent to that of people with type 2 diabetes or rheumatoid arthritis, said Dr. Rumana Islam, from Imperial College, London, UK.
Dr. Islam and her colleague Dr. Rufus Cartwright studied the records of nearly 5000 women who formed part of the 1958 Birth Cohort.
"This included all the women born in Britain in a single week," said Islam.
"They have been followed up eight times, most recently at age 50, when they were asked about the date and cause of their menopause and also their quality of life," she stated.
Out of the 4968 study participants, 370 had either spontaneous or medically induced POF.
The result showed that women with POF were more than twice as likely to report poor quality of life.
In addition to the influence of social class, there was a strong independent association with smoking.