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Placebos and Sham Treatments: How Genes Plays A Role
The finding could be considered a milestone in the quest to understand the phenomenon, which often blurs the results of clinical trials.
And the finding came despite the fact the gene is not vital to a person's response to treatment for all conditions and the experiment involved only a small number of people.
"To our knowledge, it's the first time anyone has linked a gene to the placebo effect," New Scientist quoted Tomas Furmark of Uppsala University in Sweden as saying.
For the study, the researchers enrolled 25 people with an exaggerated fear of public humiliation, also known as social anxiety disorder.
The experiment required the participants to give a speech at the start and end of an eight-week treatment-actually a placebo-which was not disclosed to them and their doctors.
It was found that ten volunteers responded to the placebo much better than the rest.
By the time the experiment was over, the anxiety scores of these participants had halved, whereas the others' stayed the same.
According to the brain scans, it was found that the activity in the amygdala, the brain's "fear" centre, had dropped by 3 per cent.
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