Japanese scientists have found that Pycnogenol, a natural plant extract from the bark of the maritime pine that grows along the coast of southwest France, helps people by enhancing healthy nitric oxide (NO) production, which leads to an increase in blood flow and oxygen supply to muscles.
As the muscles gain more nutrients and oxygen as a result of increased blood flow, their ability to cope with increased physical activity and build when subjected to regular elevated labour also improves, say the researchers.
This study suggests that when taking Pycnogenol, more NO is provided in response to neurotransmitters allowing for better expansion of arteries to carry more blood. This process serves to meet the enhanced oxygen demand of the performing muscle and avoid anaerobic metabolism, said Dr. Yukihito Higashi, lead researcher of the study that appeared in the journal Hypertension Research.
These results also lead me to determine that Pycnogenol will be a useful natural alternative therapy in various diseases in which oxidative stress is involved in the pathogenesis, added the researcher from the Hiroshima University Graduate School of Biomedical Sciences.
During the course of study, young healthy men either took 180 mg Pycnogenol or a placebo everyday. For testing Pycnogenols effect on the release of NO, an inhibitor of the amino acid L-arginine was infused in patients, which restricts the expansion of arteries in response to the neurotransmitter acytelcholine.