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Pigmentation Gene Could Be Key To Breast Cancer Survival
An international team is zeroing in on OCA2 gene for future treatment. QIMR researchers, as part of an international collaboration, have found that a gene that is most commonly associated with skin pigmentation, may influence a patient's chances of surviving cancer.
According to Professor Georgia Chenevix-Trench of Queensland Institute of Medical Research, "The variant of the gene is only a single change in the genetic sequence, but seems to have quite an impact.
"Our research focused on a specific type of breast cancer, oestrogen receptor negative breast cancer.
"Among these patients, those with the rare variation had a predicted survival rate of 83 per cent at 10 years, compared to the common variant, which we found had a predicted 60 per cent survival after 10 years."
This kind of fundamental research is vital to understanding cancer and providing effective cancer treatments.
"Traditional ways of predicting survival and treatment response in cancer patients are not always successful or accurate. Our research aims to find new factors that can account for patients who have a better or worse outcome than expected.
"Understanding these factors may lead to better prediction of survival and hopefully, improved treatment options for individuals."
This study analysed 3700 breast cancer patients for this specific change in the OCA2 genetic sequence.
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More News on: Women and Cancer, DNA Finger Printing, Breast Biopsy, Pagets disease of the breast, Mastitis, Cancer and Homeopathy, Breast Cancer Facts, Cancer Facts, Cancer, Tattoos A Body Art
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