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Osteoarthritis may be Detected by Sodium MRI
Researchers at New York University have developed an innovative way to look at the development of osteoarthritis in the knee joint-one that relies on the examination of sodium ions in cartilage.
The concentration of sodium ions, which are distributed in the body, is known to reveal the location of glycosaminogycans (GAGs) in cartilage tissues. GAGs are molecules that serve as the building blocks of cartilage and are involved in numerous vital functions in the human body.
Mapping the GAG concentration is necessary for the diagnosis and monitoring of a number of diseases as well as to determine the efficacy of drug therapies. For instance, GAG loss in cartilage typically marks the onset of osteoarthritis and inter-vertebral disc degeneration.
However, the existing techniques for GAG monitoring-based on traditional magnetic resonance imaging (MRI)-have limitations: they cannot directly map GAG concentrations or they require the administration of contrast agents to reveal the location of these concentrations.
But since sodium ions are already present in cartilage, researchers have sought to measure these ions using special MRI techniques that are non-invasive.
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More News on: Osteoarthritis, Magnetic Resonance Imaging, Corrected Sodium, Hip replacement, Geriatry-Related Diseases, Hypermobility Syndrome, Back Pain at Workplace: Prevention and Exercises, Knee Replacement Surgery, Diet, Nutrition and Supplements for Osteo-Arthritis and Rheumatoid Arthritis, Hip Replacement Surgery
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