Oral Antibiotics As Good As IV Ones In Treatment Of Severe UTI

October 22, 2007 at 5:50 PM General Health News
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Oral Antibiotics As Good As IV Ones In Treatment Of Severe UTI
Although doctors routinely use IV antibiotics to cure patients with severe urinary tract infections, a new review from suggests that oral antibiotics work just as well -- from treating acute symptoms to preventing long-term complications of UTI

In light of this evidence, more doctors might consider using oral antibiotics to treat patients with severe UTI, according to German reviewer Dr. Annette Pohl at University Clinic Freiburg.

This could potentially lead to far fewer hospitalizations, which, besides avoiding disruption for patients and families, could also considerably reduce hospital and related medical costs.

“UTIs cause a significant amount of financial burden on the medical system and families,” said Hiep Nguyen, M.D., director of robotic surgery and research at the Urological Research Center, Children’s Hospital Boston. “It costs us a couple of billion dollars a year to treat children with UTIs and that doesn’t account for the money parents lose being out of work when their child is hospitalized.”

Pohl cautions that treatment with oral antibiotics requires careful supervision to guarantee compliance and to make sure patients are tolerating oral drugs.

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

The researchers pooled data from 15 studies of 1,743 patients with severe, symptomatic UTI who received either oral or IV antibiotic treatment. Nine studies involved children, with six studies focusing on children less than one year old. Of the remaining six studies, two comprised women only, including one study of pregnant women.

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