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Opioids Relieve Chronic Pain With Little Addiction Risk If Used as Prescribed

by Rajshri on  January 22, 2010 at 6:34 PM Research News
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Opioids Relieve Chronic Pain With Little Addiction Risk If Used as Prescribed
Many older adults hesitate to take opioids for fear of addiction despite having to cope with chronic non-cancer pain.

However, a new review finds that taking opioids long term is associated with clinically significant pain relief in some patients with a very small risk of addition.


"Not every patient has adequate pain relief, though, and side effects are intolerable for others," said lead review author Meredith Noble.

"There is a lack of consensus that opioids are safe and effective for people with chronic severe non-cancer pain," Noble said. "We wanted to look at studies that treated people for six months or longer, given that chronic pain can go on for years. This review includes studies of individuals on opioids for as long as 48 months."

Noble is a senior research analyst at ECRI Institute, one of 14 evidence-based Practice Centers in the country under the U.S. Agency for Healthcare Research and Quality.

The review appears in the latest issue of The Cochrane Library, a publication of the Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

Noble and her colleagues reviewed the findings of 26 clinical studies comprising 4,893 participants. This review updates a review published in the Journal of Pain and Symptom Management in 2008.

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