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Obstructive Sleep Apnea Raises Sudden Cardiac Death Risk
OSA is a condition that disrupts breathing during sleep and is associated with obesity. The new study identified OSA as one of two traits that increase the risk of SCD.
The other is age - patients who are 60 years old or older.
If further studies confirm these findings, OSA would join established risk factors such as smoking, obesity, high cholesterol and high blood pressure.
Doctors have suspected for years that OSA might be implicated in SCD because of evidence that low oxygen alters the blood vessels in a way that promotes heart disease.
Mayo Clinic cardiologist Apoor Gami, M.D., the lead author of the study, said that this is the first large study to rigorously test the hypothesis.
Virend Somers, M.D., Ph.D., the studys principal investigator, said: Nighttime low oxygen saturation in the blood is an important complication of obstructive sleep apnea".
Our data showed that an average nighttime oxygen saturation of the blood of 93 percent and lowest nighttime saturation of 78 percent strongly predicted SCD, independent of other well-established risk factors, such as high cholesterol.
These findings implicate OSA, a relatively common condition, as a novel risk factor for SCD, Somers
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