Obesity Pill Zimulti Increases Depression, Suicidal Thoughts

by Medindia Content Team on  June 14, 2007 at 2:21 PM Obesity News
RSS Email Print This Page Comment
Font : A-A+

Obesity Pill Zimulti Increases Depression, Suicidal Thoughts
Boffins conducting clinical trials of obesity pill Zimulti found that it increases suicidal thoughts in patients. Reviewers for the US Food and Drug Administration (FDA) said that though the 20-milligram dose of the drug, led to significant weight loss over one year when taken with a low-calorie diet, there was still cause for concern over depression and a high drop-out rate in clinical trials.

"(Zimulti) was shown to reduce body weight by approximately 5% relative to diet alone during trials of more than 6000 moderately overweight and obese subjects", the New Scientist quoted the FDA reviewers, as saying.

Known generically as rimonabant, the drug is already sold in 18 countries under the name Acomplia. "We remain concerned about rimonabant's adverse event profile, specifically adverse psychiatric reactions," an FDA staff summary said.

The trials showed that in people who took the drug were twice as likely to develop depression than those who received a placebo. However, the drug's manufacturer Sanofi-Aventis insisted that though more rimonabant patients reported suicidal thoughts, the drug's benefits "clearly outweigh the defined risks that are manageable in clinical practice".

Rimonabant works by blocking food craving signals in the brain. Sanofi, a French drug maker, developed the drug to target the brain receptors that trigger intense hunger after marijuana use.

Source: ANI
LIN/S

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Bariatric Surgery Obesity Depression Vasectomy Body Mass Index Stress Relief Through Alternative Medicine Andropause / Male Menopause Liposuction Pregnancy and Complications Bereavement 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive