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Obesity, Memory Problems Link May Be Linked To Insulin Sensitivity
The results provide further evidence that a healthy lifestyle at midlife could lead to a higher quality of life later on, especially as new drugs and treatments allow people to live longer.
"The good thing about insulin sensitivity is that it's very modifiable through diet and exercise," says psychology graduate student Mitzi Gonzales, who co-authored the paper published in the journal Obesity with Assistant Professor Andreana Haley and other colleagues.
To better understand why midlife obesity is linked to higher risk of cognitive decline and dementia in old age, the researchers had middle-aged adults between 40 and 60 years of age complete a challenging cognitive task while undergoing functional magnetic resonance imaging (fMRI).
While obese, overweight and normal-weight participants performed equally well on the task, obese individuals displayed lower functional brain response in one brain region, the inferior parietal lobe.
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