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Obese People Fight With Their Genes
The study is the first to confirm that severe obesity in otherwise physically health individuals can be caused by a rare genetic variation involving deletion of DNA, say the authors.
Until now, genes linked to weight gain have had a relatively modest effect on fat accumulation, of just a kilo (two pounds) or less.
Other genetic gaps or variations involved in chronic obesity may yet be uncovered, lead author Philippe Froguel, a professor at Imperial College London, said in a press release.
"Although the recent rise in obesity in the developed world is down to an unhealthy environment, with an abundance of unhealthy food and many people taking very little exercise, the difference in the way people respond to this environment is often genetic," he said.
"It is becoming increasingly clear that for some morbidly obese people, their weight gain has an underlying cause.
"If we can identify these individuals through genetic testing, we can then offer them appropriate support and medical interventions, such as the option of weight-loss surgery, to improve their long-term health."
Source-AFP
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