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Novel Therapies To Treat Breast And Lymph Cancer Developed
The women treated with BSI-201 survived 9.2 months on average, including 6.9 months in which the cancer did not spread, compared to an average survival of 6.9 months and 3.3 months in which the cancer was in check for those who were treated solely with chemotherapy.
The second clinical study involved 54 women suffering from advanced breast cancer linked to the gene mutation BRCA1 or BRCA2. They were treated with the PARP blocker Olaparib made by the Anglo-Swedish pharmaceutical AstraZenica. There was no control group.
The test showed that 40 percent of the patients who took the drug experienced a reduction in their tumors, said Andrew Tutt, a cancer specialist at Kings College in London.
In another study presented here researchers examined a vaccine on patients over eight years that targeted follicular non-Hodgkin's lymphoma, a particularly aggressive form of lymphatic cancer.
The study found that patients who received the BiovaxID vaccine experienced on average disease-free survival of approximately 44 months, compared to about 30 months for patients who received a control vaccine, an increase of 47 percent.
The BiovaxID vaccine is patient-specific, in that each dose must be individually manufactured from tissue obtained from a patient's own cancerous tumor.
"With this vaccine, we've now moved into an era where we can safely use a patient's immune system to effectively fight follicular lymphoma and enhance the response to conventional chemotherapy" said lead study author Stephen Schuster.
"Because this vaccine uniquely recruits the patient's immune system to seek and destroy only tumor B-cells, this approach may be applicable to the treatment of other B-cell lymphomas," Schuster added.
Source-AFP
ARU
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