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Noninvasive Way To Determine Estrogen Levels In Infants, Thanks To Diapers!
The new technique, previously used in nonhuman primates, will allow researchers to learn more about the association between estrogen levels in human infants and their long-term reproductive development as well as the development of sex-specific behaviors, such as toy preference or cognitive differences. Whats more, the method will also allow researchers to look at how early disruption of the endocrine system affects long-term maturation, a growing concern among researchers and physicians.
Surprisingly little is known about hormone levels during human infancy. Previous human research has focused on the measurement of hormones in blood, urine and saliva. The new data are the result of using fecal samples collected from cotton diapers. With this novel approach, the researchers successfully measured the fecal levels of estradiol, a type of estrogen.
The well-known importance of estradiol's role in postnatal development of the body, brain and behavior has in recent years raised specific concerns about how exogenous estrogens, or environmental estrogens, such as those found in soy, fruits and vegetables, plastics and common household items, affect lifelong health.
The development of robust, noninvasive methods to measure these hormones in infants allows us to further investigate the association between postnatal hormone production and the development of sex-specific biology and behavior, says Michelle Lampl, PhD, MD, Emory University Samuel Candler Dobbs professor of anthropology, and senior author of a paper in Frontiers in Systems Biology describing the new method.
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