Newer Antipsychotics Useless in Treating Child and Adolescent Schizophrenia

by Rajashri on  September 15, 2008 at 2:32 PM Drug News   - G J E 4
 Newer Antipsychotics Useless in Treating Child and Adolescent Schizophrenia
A new study funded by the National Institutes of Health's National Institute of Mental Health (NIMH) has found that new antipsychotic medications were not effective in treating child and adolescent schizophrenia. In fact the study says they may even cause side effects.

The Treatment of Early Onset Schizophrenia Study (TEOSS) involved 116 youth between 8 and 19 years old. All participants were diagnosed with early onset schizophrenia.

The patients were given olanzapine (Zyprexa) or risperidone (Risperdal) or older conventional antipsychotic molindone (Moban) plus benztropine on a random basis. After eight weeks it was found that 50% of the kids taking the older drugs improved, while 46 percent taking risperidone improved, and 34 percent taking olanzapine improved.

"Schizophrenia and schizophrenia-related disorders are rare in childhood. But when they do occur, those afflicted generally have more severe symptoms and a worse prognosis than those who develop the disorder in adulthood," said NIMH Director Thomas R. Insel, M.D. "The newer atypical antipsychotics are often used to treat these children, but until now, it has been unclear how effective and safe they really are in children. The side effects of the newer medications should be factored into making treatment decisions."

The details appear in the American Journal of Psychiatry.

Source: Medindia

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Lilly Zyprexa ' Chemical Straitjacket' Use by Children.
Zyprexa,as well as the other atypical antipsychotics, are being prescribed for children, even though this is an unapproved, off-label use. Eli Lilly has been charged in allegedly pushing the drug for children in more than one state.

A report by Dr. Cooper at Vanderbilt University states that 2.5 million children are now taking atypical antipsychotics.

St. Petersburg Times Reports on Zyprexa A risky drug may get wider marketThe FDA may approve Zyprexa for kids, despite its significant side effects in adult use.

guest Monday, September 15, 2008

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