Newborns With Blood Disorder That Affects Immune System Identified by Screening Method

by Rajshri on  December 13, 2009 at 10:28 AM Child Health News
  •   Print
  •   Share
  •   Comments
  •  Text 
 Newborns With Blood Disorder That Affects Immune System Identified by Screening Method
A study in the December 9 issue of JAMA says that the testing of DNA from a statewide blood screening program for newborns in Wisconsin was able to identify infants with T-cell lymphopenia, a blood disorder that affects the child's immune system, a disease in which early identification is important.

Infants with severe T-cell lymphopenia (abnormally low level of white blood cells), including severe combined immunodeficiency (SCID), often appear normal at birth and have no family history of immunodeficiency. "Consequently, many infants with severe T-cell deficiencies are not identified until life-threatening infections occur. This is an important issue because the long-term prognosis of infants with SCID and other serious immunodeficiencies is markedly improved if the diagnosis is made early, before the onset of serious infections," the authors write. They add that the administration of some vaccines that are recommended in early infancy can cause serious infection in infants with T-cell lymphopenia, which could be avoided with early detection.

John M. Routes, M.D., of the Medical College of Wisconsin and Children's Research Institute, Milwaukee, and colleagues conducted a study to examine if determining the number of T-cell receptor excision circles (TRECs) using DNA extracted from dried blood spots on newborn blood screening (NBS) cards could detect T-cell lymphopenia in newborn infants in a statewide screening program. Between January 1 and December 31, 2008, the Wisconsin State Laboratory of Hygiene screened all infants born in Wisconsin for T-cell lymphopenia by quantitating the number of TRECs contained in a portion of the NBS card, with the cut-off number being TREC values of less than 25/μL. T-cell lymphopenia was confirmed by further testing.

Page 1 Page 1 | 2  Next
 Email Email   RSS Feeds RSS Feeds   Print this page Print   Save this page Save   Link Link   Syndicate Syndicate   Comments Comments   Bookmark and Share
 
Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
X

Medwonders Health Network

  • Health News Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Archive
Date :
Category :
Keyword :
  • News Quick Links
News Central Health Watch
Latest Health News Health In Focus
News Category (500+) Breaking Health News
Popular News Celebrating Life
Health News and Press Release Medindia - Exclusive
News Photo Gallery India Special
News Video Gallery Lifestyle and Wellness
News From Other Resources
News Categories:  
Senior Health Center

Child Health Related News

» Obesity Raises Cranial Disorder In Kids That May Cause Blindness » Study Says Babies Learn from 'Just Right' Experiences
» Study Says Softening Agent Used in PVC Floor Materials Increases Risk of Asthma and Allergies in Infants » Childhood Wheezing Not Linked to Viral Infections in Infancy
» Letting Infants Cry Could Prove Detrimental to Health » Investigate Crib Deaths, Orders Bengal Government
» C-section Doubles Childhood Obesity Risk » Weight Loss May Improve Sleep-disordered Breathing in Obese Kids
Read More >>