The results of the Southeastern study are published in American Academy of Ophthalmology. Dr. H. Dwight Cavanag, senior author of the study and vice chairman of ophthalmology and associate dean for clinical services at Southeastern, said study results provide a firm biological foundation for increased prospective safety of the new silicone hydrogel lens materials.

According to Cavanag and his study, the significance of out study is that for the first time we have a scientific-based rationale that has passed peer review at high levels that exactly predicts our current epidemiological risk pattern and strongly suggests that these new lenses will be the breakthrough in reducing risk for infection.

Cavanag said conventional contact lenses disturb the surface of the cornea, thereby allowing pathogenic bacteria, such as Pseudomonas aeruginosa, to bind to the corneal surface cells and potentially initiate infection.The most significant and devastating clinical complications among contact-lens wearers have been corneal ulcerationand infection, which can lead to permanent visual loss.

He said that this is the first randomised, prospective, masked clinical study with contact lenses that demonstrates significant difference in bacterial binding to the cornea as a function of the oxygen transmission of the lenses themselves. This means that there are really small amounts of increased bacterial binding seen with extended-wear, even up to 30 nights, with the novel contact-lens materials that transmit high amounts of oxygen to the eye as compared to presently available conventional