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New Tuberculosis (TB) Vaccine Expected to be Ready by 2020

by VR Sreeraman on July 19, 2010 at 6:15 PM Respiratory Disease News

The current tools are not enough to control tuberculosis epidemic. The 2009 World Health Organization (WHO) Global Tuberculosis Control Report says that the incidence of TB per capita continues to go down since 2004 however the decline is just one per cent per year which implies that TB will not be eliminated for centuries if we conduct 'business as usual'.

New Tuberculosis (TB) Vaccine Expected to be Ready by 2020

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The existing BCG vaccine which came into the market in 1921, has limited effectiveness in preventing people from TB. Further, the BCG vaccine which is used to prevent childhood TB may not be safe for children living with HIV. That is why Aeras Global TB Vaccine Foundation and other agencies including Bill & Melinda Gates Foundation are pushing hard to accelerate research and development of safe and effective TB vaccines.

Currently there are seven vaccine candidate products in different stages of the research pipeline around the world.

One phase-III clinical trial in Tanzania which was sponsored by a US University, studied adults who were living with HIV, to see if there was any reduction in disseminated TB in that population. The promising results were announced in October 2008. "Aeras' vaccine advisory committee has looked at this vaccine as a first step. Aeras is providing our manufacturing expertise to see if it can be made at a larger scale" said Peg Willingham, Senior Director, External Affairs, Aeras Global TB Vaccine Foundation.

"In our research pipeline at Aeras we have six vaccine candidate products" shares Peg Willingham.

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New Tuberculosis (TB) Vaccine Expected to be Ready by 2020

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