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New Treatment for Muscular Dystrophy is Safe and Effective
The protein has shown promising results as a potential therapeutic target for treating muscular dystrophy in animal studies, and its inhibition resulted in increased muscle mass and strength.
The new study, which is the first to evaluate a myostatin inhibitor in patients, assessed its safety in adults with muscular dystrophy and found that it was well-tolerated.
The researchers conducted a double blind, randomized study of 116 patients with muscular dystrophy.
They divided patients with multiple different types of muscular dystrophy into four groups given sequentially higher doses of a myostatin inhibitor called MYO-029.
The researchers randomized each group to receive the test drug or a placebo in a 3:1 ratio.
The drug or placebo was given intravenously every two weeks for six months, after which the patients were followed for three months.
While the aim of the study was to test for safety, muscle strength and mass were also assessed.
The researchers found that safety assessments, including vital signs, laboratory tests and physical examination showed no significant differences between treatment and placebo groups.
They also found that there were no side effects to skeletal, smooth or cardiac muscle, and the most significant side effects related to the treatment were hypersensitivity skin reactions.
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More News on: Muscular Dystrophy, Genetic Testing of Diseases
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04/06/2012
My 2 uncles are suffering from the same disease. They are 45 and 50 yrs old. I would like to know if there any further advancement in finding cure to this disease.
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