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New Study May Lead To Synthesizing Male Contraceptive Pill
Mark Platt, an assistant professor of Chemistry and Chemical Biology at Rensselaer Polytechnic Institute, says that his findings provide important clues into the still-mysterious process of capacitation, the process by which sperm acquire the ability to fertilize an egg, including why some otherwise healthy males might encounter fertility issues.
He says that his work may have implications for the development of entirely new contraceptive, even a male version of the birth control pill.
"Much has been done to understand capacitation, but with the tools that we have within the lab we can now identify how specific sites on individual proteins are modified during this process. With this knowledge we can develop a deeper understanding of the molecular mechanisms required to provide sperm with fertilizing competence...Based upon some of our additional work, a few of these sites appear to be essential to carrying out the process of capacitation," he says.
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