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New Method To Test Efficacy Of Cranberry Products
Such infections are caused by bacterial adhesion (bacteria growth) on cells in the bladder. To maintain urinary tract health, especially for those prone to UTIs, daily consumption of 36mg of cranberry proanthocyanidins (PACs) has shown effectiveness in inhibiting bacteria from adhering to bladder cells, multiplying and consequently causing infection. This amount of PACs can be easily consumed in a 9-10 oz (266-296 ml) serving of 27% cranberry juice cocktail.
PACs are small molecules (catechin or epicatechin) linked together to form larger polymers. The PACs in cranberries contain a high proportion of what are called "A-type double linkages" between the catechin or epicatechin molecules. Other food sources of PACs that do not contain these linkages (chocolate, grapes, apples and green tea) do not elicit the bacterial anti-adhesion activity.
With some cranberry product testing methods, overestimation of up to five times the PAC level have been reported. A study published today in the Journal of the Science of Food and Agriculture uses the new BL-DMAC method of quantifying PAC levels in cranberry products which the authors claim can now serve as the standard industry method, allowing product manufacturers to provide accurate PAC levels.
To evaluate this method, 11 samples of cranberry products were obtained (five from U.S. sources and six from European sources) for PAC quantitation analysis. Powdered samples were coded and sent blinded to five different analytical laboratories (three in the U.S., one in China and one in Europe) for analysis by the BL-DMAC method. Each laboratory reported statistically consistent results of PAC levels.
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