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New Medication for Cystic Fibrosis by Vertex

by Dr. Trupti Shirole on  February 26, 2011 at 1:30 PM Drug News   - G J E 4
A promising new medication for cystic fibrosis which is to be taken twice a day has fared well in the mid-stage clinical trials. The research was published by Vertex in its press release on 23rd February 2011. Cystic fibrosis is a genetic disease and can cause serious infections and digestive problems. It has been estimated by the Cystic Fibrosis Foundation that about 30,000 US citizens while 8,500 UK citizens are affected by the disease.
 New Medication for Cystic Fibrosis by Vertex
New Medication for Cystic Fibrosis by Vertex
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161 patients with a specific type of cystic fibrosis were part of the study. They were asked to take this medication twice a day and it was seen that on an average their lung function improved by 10% as compared to those patients who were given placebo pills. This improved lung function is better than the other treatments like inhaled medicines or enzyme replacement therapy for the disease. Improvements in other areas like weight gain and reduction in respiratory symptoms were also seen. Patients who took this medication showed 55% reduction in the probability of pulmonary exacerbation.

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Drug maker Vertex will submit this new medication for approval to the US FDA. The currently available drugs only target the symptoms of cystic fibrosis while this new drug attempts to correct the malfunctioning protein in the mutated gene's cell membrane that allows cystic fibrosis to flourish.

Source: Medindia
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