New Discovery may Inhibit Growth of Breast Tumors

by VR Sreeraman on  January 4, 2011 at 7:24 PM Cancer News
RSS Email Print This Page Comment
Scientists have made a new discovery, which may become a new weapon in fight against breast cancer.

For the first time, researchers at Wake Forest University Baptist Medical Center have shown that a peptide found in blood and tissue inhibits the growth of human breast tumors in mice.
 New Discovery may Inhibit Growth of Breast Tumors
New Discovery may Inhibit Growth of Breast Tumors
Advertisement

Patricia E. Gallagher and E. Ann Tallant demonstrated that the peptide angiotensin-(1-7) attacked breast cancer in two ways: by inhibiting the growth of the breast cancer cells themselves and by inhibiting the growth of cancer-associated fibroblasts (CAFs), cells found in the tumor microenvironment-the tissue surrounding the tumor.

Advertisement
In this study, mice were injected with human breast cancer cells to form the two most common types of breast tumors - estrogen-receptor and HER2 sensitive.

Once the tumors grew, the mice were injected with either angiotensin-(1-7) or saline for 18 days. In the mice treated with angiotensin-(1-7), there was a 40 percent reduction in tumor size as compared to the saline-injected mice.

Breast tumor fibrosis also was reduced by 64 to 75 percent in the mice treated with the peptide as compared to the saline-injected mice.

The finding has been recently published in the journal Cancer Research.

Source: ANI
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Mastitis Breasts - Structures and Types Breast Lumps Breast Lumps-Screening Breast Enhancement Oil 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive