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New Approaches to Understand Obesity and Weight Loss: Study
According to the study reported in the journal Nature, the number of fat cells in a person is established during adolescence and stays the same regardless of obesity in later years.
The rising rate of obesity has focused a lot of scientific attention on the "adipocyte", the cell type that makes up the bulk of our bellies and waistlines.
When we are getting fatter, these fat cells are actually expanding in size, but experts were not sure if the number of adipocytes could increase and decrease as well.
The Swedish researchers first tested several hundred children, adolescents and adults of different ages and found that while fat cell numbers increased through childhood, the number of fat cells stayed fixed by the time adulthood was reached.
They studied the possibility that fat cell numbers could change in extreme circumstances by taking samples of fat from patients about to undergo radical weight loss.
Fat cells were taken from those about to undergo "gastric banding"an operation performed to help very obese patients lose weight by reducing the size of the stomach.
After the weight loss was complete, another sample of fat was taken to assess if the overall number of fat cells had decreased.
The researchers found that the level of fat cells had stayed the same even after the weight loss program thus providing an insight into why fat people find it so hard to lose weight, even after a stringent diet.
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