New Approach may Provide Breakthrough in Treating Lupus

December 17, 2007 at 4:31 PM Research News
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New Approach may Provide Breakthrough in Treating Lupus
Two new targets for drugs to control lupus have been identified, and may provide a breakthrough in the treatment of the disease.

The study by investigators at Hospital for Special Surgery further enables patients to control the disease with fewer side effects, provided that drugs that can work specifically on these sites are developed by companies.

Lupus is an autoimmune disease affecting many parts of the body, including the skin, joints, heart, lungs, blood, kidneys and brain. The main feature of this disease is inflammation that is characterized by pain, heat, redness, swelling and loss of function.

However, in majority of the people, this disease influences only a few organs with mild symptoms, but in others, lupus can lead to serious and critical problems.

If the statistics of the Lupus Foundation of America are believed, an estimated 16,000 Americans develop lupus each year.

The study was led by Lionel Ivashkiv, M.D., director of Basic Research at Hospital for Special Surgery in New York City.

“The study identifies very good therapeutic targets, and what needs to be done is identify better candidate drugs,” Nature Immunology quoted Dr. Ivashkiv.

The drugs developed by researchers are mainly aimed at blocking interferon as extraordinarily high levels of interferon-alpha may lead to lupus.

However, these drugs have immunosuppressive side effects making patients susceptible to a number of illnesses and infections, of which some can prove to be deadly.

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guest

12/19/2007

we already have a clinically proven & safe treatment for lupus but no one seems to care because it doesn't involve drugs - it's called UVA1 phototherapy


guest

08/22/2009

Can you tell me more about the photo therapy




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