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Nanodiamonds Offer Safer, Effective Drug Delivery System
October 14, 2007 at 2:26 PM
Research News
Writing about their findings in the journal Nano Letters, the researchers said that the drug delivery system with nanodiamonds would come without the negative effects liked with the current drug delivery agents.
The researchers also said that apart from cancer drugs, the nanodiamonds could also be used for fighting tuberculosis or viral infections.
They have also referred to a series of genetic studies that have confirmed that nanodiamonds do not cause cell inflammation once the drug has been released, and only bare diamonds are left.
By contrast, say the researchers, drug delivery materials that are in use currently can cause inflammation, a serious complication that can predispose a patient to cancer, block the activity of cancer drugs, and even promote tumour growth.
There are a lot of materials that can deliver drugs well, but we need to look at what happens after drug delivery, said Dean Ho, assistant professor of biomedical engineering and mechanical engineering at Northwesterns McCormick School of Engineering and Applied Science, who led the research.
How do cells react to an artificial material left in the body? Nanodiamonds are highly ordered structures, which cells like. If they didnt, cells would become inflamed. From a patients perspective, this is very important. And thats why clinicians are interested in our work, he added.
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