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Nano 'Bombs' Filled With Lauric Acid To Fight Acne
"Precisely controlled nano-scale delivery of drugs that are applied topically to the skin could significantly improve the treatment of skin bacterial infections. By delivering drugs directly to the bacteria of interest, we hope to boost antimicrobial efficacy and minimize off-target adverse effects," said Zhang. "All building blocks of the nano-bombs are either natural products or have been approved for clinical use, which means these nano-bombs are likely to be tested on humans in the near future."
Zhang noted that nano-scale topical drug delivery systems face a different set of challenges than systems that use nanotechnology to deliver drugs systematically to people.
Pornpattananangkul and UC San Diego chemical engineering undergraduate Darren Yang confirmed, in 2009 in the journal Biomaterials, the antimicrobial activity of nano-scale packets of lauric acid against Propionibacterium acnes.
Pornpattananangkul, who is originally from Thailand, said that it's just a coincidence that her research involves a natural product produced by coconuts, a staple of Thai cuisine.
From a new solar concentrator design to balancing robots, experimental acne drugs, and wireless heart and brain sensors, UC San Diego graduate engineering students are developing next generation technologies and therapies to address the environmental, health and computing needs of society. These students presented their cutting edge projects at the 29th Annual Jacobs School of Engineering Research Expo on April 15. The theme of this year's Expo is Renewables and America's Energy Future.
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