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Muscle Mass Doubled by Stem Cell Transplant
The cells not only repaired the injury within days, they caused the treated muscle to double in mass and sustain itself through the lifetime of the transplanted mice.
"We found that the transplanted stem cells are permanently altered and reduce the aging of the transplanted muscle, maintaining strength and mass," said Professor Bradley Olwin of CU-Boulder's molecular, cellular and developmental biology department.
"With further research we may one day be able to greatly resist the loss of muscle mass, size and strength in humans that accompanies aging, as well as chronic degenerative diseases like muscular dystrophy," he added.
Stem cells have the ability to renew themselves through cell division and differentiate into specialized cell types.
"The environment that the stem cells are injected into is very important, because when it tells the cells there is an injury, they respond in a unique way," he said.
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