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Multiple Sclerosis More Aggressive in Kids Than Adults
The MRI measured two types of brain tissue damage-T1-lesion volume, which shows "black holes," or hypointense lesions, which are areas of permanent axonal damage; and T2-lesion volume, which shows the total number of lesions (lesion load) and overall disease burden.
Both of these measures indicated that MS is more aggressive in children in the early stages, said the researchers.
"This corresponds with recent data that suggest a higher lesion burden in pediatric MS than adult-onset MS. These findings are somewhat surprising, considering we have assumed that children generally have a greater capacity for central nervous tissue repair," they added.
"Our findings, which are limited to a cross-sectional study design, suggest that children have a somewhat better reserve and functional adaptability than adults, but less support for a better remyelination process. However, the remyelination process may require a more in-depth prospective analysis," said Weinstock-Guttman.
She said that the data supports the need for early diagnosis and therapeutic intervention in paediatric MS patients.
The study was published online November 5, in Brain.
Source-ANI
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More News on: Development Milestone, Height and Weight-Kids, Chemotherapy, Chemotherapy Drugs, Infectious Mononucleosis, Multiple Sclerosis Treatment and Modify, Optic Neuritis, Autoimmune Disorders
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