The accumulation of peptides, which are short compounds containing two or more amino acids, is an indication that the enzyme needed to fully break down certain proteins is inhibited or missing, and can have an opium-like effect on the brain, according to Reichelt.
Much international research has been done linking such protein disorders to cases of autism and schizophrenia, and a growing number of studies also hint that some cases of ADHD are connected with the digestive problem.
There is however a lot of scepticism to the theory in medical circles, with many doctors believing medication like Ritalin is the best way to treat the condition.
Noedland acknowledges the Stavanger project does not meet all scientific standards, claiming the main problem is the lack of comprehensive studies on how many ADHD children suffer from peptide abnormalities.
"There is no reason to put everyone with ADHD on a diet if only 10 percent of them have protein imbalances," he says.
The children in the Stavanger project all followed a strict casein-free diet the first year, and the results were overwhelmingly positive, Noedland says, pointing out that 22 of the 23 families reported clear improvements in their child's behaviour and attention-span.
A number of the children have since stopped following the diet for different reasons and some were put on medication, but after eight years six were still strictly avoiding all milk products and several had also cut out gluten, which is found in wheat, rye, barley and to some extent oats.
"We see a clear difference between those who stopped and those who stayed on the diet," Noedland says.
"Seeing these kids going from one day not being able to learn a thing to the next day being receptive; as a teacher that's a wonderful feeling," says Kristine Fosse, one of the educators involved in the project.
To illustrate her point, Fosse pulls out a writing test by a six-year-old boy who took part in the project.
The boy was asked to write his numbers after involuntarily breaking his diet and ingesting milk on September 22, 1996. The result was a confused and jumbled mess of squiggly lines. Just two days later, again strictly steering clear of casein, he repeated the exercise, this time writing four clearly legible numbers in an even line.
"It's incredible. We've seen intelligence tests that had gone steadily down suddenly turn around and go back up" after a change of diet, says Ann-Mari Knivsberg, who covers the research end of the Stavanger project.
One of the children who still avoids milk and gluten, 17-year-old Sigbjoern, says any lapse in his diet affects his performance in school.
"I can tell right away when I've eaten something I shouldn't. It's really hard to concentrate. I'm always careful before tests," he says, taking a big bite of gluten and milk-free carrot cake.
Considered a hyperactive problem child with retarded development in nursery school, Sigbjoern today ranks among the best students in his class.
"He had a slow start and a lot of trouble learning to begin with, but by secondary school he was really doing well," says Sigbjoern's mother Grete, 52.
Both Grete and Rita asked that their families' last names not be used for fear of stigmatisation.
"It is considered shameful to have ADHD," Grete says. "When they're on a diet they're just like everyone else. Just look at them. We have two normal, great kids. I'm eternally grateful that Sigbjoern was included in the project."
Hundreds of other Norwegian children with ADHD, mainly in and around Stavanger, have in recent years been put on milk-free diets to help deal with their condition, but Fosse complains many doctors don't inform parents of the option.
"We want to get the word out that this can be an alternative. Parents have to do a lot of searching before they get this information," she says.
"The scepticism is infuriating. I'm glad I have a good education and can stand up for myself when I meet doctors who ridicule what I'm doing," says Grete, putting her arm around Sigbjoern's shoulder.
"I mean, as a parent, wouldn't you want to at least try switching your child's diet before medicating him?"
Source-AFP
SUN/K