Forty-five infants had a first episode of late-onset sepsis.
The researchers found that overall, late-onset sepsis occurred less frequently in the BLF and BLF plus LGG groups (9/153 [5.9 percent] and 7/151 [4.6 percent], respectively) than in the control group (29/168 [17.3 percent]).
The decrease occurred for bacterial as well as fungal episodes.
The sepsis-induced risk of death was significantly lower in the two treatment groups. No adverse effects to treatment occurred.
"This study has demonstrated that supplemental BLF, either alone or in combination with LGG, reduces first episodes of late-onset sepsis in VLBW infants," concluded the authors.
The study has been published in the latest issue of JAMA.
Source-ANI
RAS