Each of the 300 post-menopausal women took three cognitive tests: The Mini-Mental Statement Examination, a common test for evaluating the global cognitive status, a clock-drawing test to determine the women''s executive function (planning, problem-solving, verbal reasoning, etc.); and the Boston Abbreviated Test to assess the women''s memory.
The researchers found that BMI was positively correlated with higher levels of cognition. They also found an equal correlation between obesity-related waist circumference and global cognition.
But where does estrogen fit in? "Where there is increased adipose tissue , there is increased estrogen," said Dr. Zilberman. "My hypothesis is that estrogen may be protective of cognitive function in this case."
According to Dr. Zilberman, the possibility that naturally occurring estrogen from a woman''s own fat cells may help preserve cognition flies in the face of current medical advice. "Based on previous studies, many research institutions have decided against recommending estrogens as a preventive intervention in cognitive impairment or dementia," she said. "That''s what makes our findings so important."
NOTE TO EDITORS: The Physiology of Cardiovascular Disease: Gender Disparities conference will be held October 12-14 at the University of Mississippi in Jackson. The press is invited to attend. For additional information, or to receive a copy of Dr. Zilberman''s abstract, please contact Donna Krupa at 301.634.7209 or
dkrupa@the-aps.org.
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Physiology is the study of how molecules, cells, tissues and organs function to create health or disease. The American Physiological Society has been an integral part of the discovery process since it was established in 1887. To keep up with the science, follow @Phyziochick on Twitter.
Source-Newswise