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Mechanism of Human Puberty, Fertility may Be Provided by Zebrafish Study
The researchers are hopeful that their study would enable better ways to help children who do not mature sexually.
"They can go to the right place but take too long; delayed puberty suggests they got there late," says Dr. David J. Kozlowski, developmental geneticist in the Medical College of Georgia Schools of Medicine and Graduate Studies.
"They can go to the wrong place. They can go to the right place and make the wrong connections, or not enough of them go to the right place. All sorts of things can go wrong and result in clinical defects," he adds.
Dr. Lawrence C. Layman, an expert on delayed puberty, believes that improved understanding and treatment may help scores of people who have to face puberty problems due to central nervous system abnormalities.
It may be crucial to improving birth control and fertility treatments, he says.
The researchers have revealed that puberty begins when the hypothalamus in the brain begins releasing more gonadotropin releasing hormone (GnRH).
This hormone stimulates the pituitary gland to make follicle stimulating hormone, and luteinizing hormone that prompt ovaries to produce oestrogen and eggs, and testes to produce testosterone and sperm.
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