The results showed that maintenance therapy did not stop liver disease from progressing.
In addition, researchers were startled by the rate of progression of liver disease. After four years, 30 percent of the patients in both the treatment and control groups had developed liver failure, liver cancer, or had died.
Among those with milder cirrhosis, 10 to 12 percent developed severe liver disease, also unexpected.
"Hepatitis patients in these circumstances got very ill over the course of four years, surprisingly so," said Di Bisceglie.
"The lesson we learned is that once chronic hepatitis C gets to the stage of advanced fibrosis, patients can decline rapidly," he added.
The study is published in the New England Journal of Medicine.
Source-ANI
SPH