MRI Better Than Mammography in Diagnosing Breast Cancer at Early Stages

August 12, 2007 at 3:41 PM Cancer News
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MRI Better Than Mammography in Diagnosing Breast Cancer at Early Stages
A study in the Lancet could lead to a change of paradigm in the early diagnosis of breast cancer. It states that magnetic resonance imaging (MRI) is substantially more accurate than mammography in diagnosing very early stages of breast cancer. Up to now MRI was thought to be hardly suited for the detection of such 'ductal carcinoma in situ (DCIS). Researchers at the University of Bonn have now come to a completely different conclusion. In the past five years they examined more than 7000 women with both methods. In a total of 167 women the doctors found early forms of breast cancer – 152 (92 %) of these were found using MRT, 93 (56 %) with mammography.

Breast cancer forms in the cells which line the inside walls of the milk ducts. The tumour initially remains in the milk duct and is therefore called " intraductal cancer" or DCIS (ductal carcinoma in situ). Although even at this stage it is called a carcinoma, it behaves actually like a benign disease, which can always be treated successfully by operating on it. Only when the tumour grows out of the milk ducts into the breast’s glandular tissue can it spread via blood and lymph vessels in the body. 'If we find DCIS and remove it we can prevent the formation of “real” breast cancer,' the Bonn radiologist Professor Christiane Kuhl explains. 'That way we prevent the development of a disease that is often life-threatening.'

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