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Long-term Survival Not Improved by IV Drug Treatment for Out-of-hospital Cardiac Arrest
"In the intravenous group, 44 of 418 patients (10.5 percent) survived to hospital discharge vs. 40 of 433 (9.2 percent) in the no intravenous group. Survival with favorable neurological outcome was 9.8 percent for the intravenous group and 8.1 percent for the no intravenous group," the authors write. "The cumulative postcardiac arrest survival rate at 7 days was 14.6 percent for patients in the intravenous group vs. 12.8 percent for patients in the no intravenous group, 11.3 percent vs. 8.8 percent, respectively, at 1 month, and 9.8 percent vs. 8.4 percent at 1 year."
The researchers note that after adjustment for ventricular fibrillation, response interval, witnessed arrest, or arrest in a public location, there was no significant difference in survival to hospital discharge for the intravenous group vs. the no intravenous group. "Larger trials examining resuscitation without intravenous access and drug administration, as well as of existing or new drugs, appear to be justified."
Source-Eurekalert
RAS
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More News on: Drug Toxicity, Palpitations And Arrhythmias, Cardiac Catheterization, Signature Drug Toxicity, Statins, Cardiomyopathy
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