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Liver Patients may also Experience Problems With Memory
Loyola neuropsychologist Christopher Randolph, and colleagues found that 54 percent of 301 cirrhosis patients who were tested scored below the 10th percentile for their age and education on a test that measures neurocognitive abilities.
"Neurocognitive impairment is a major issue in patients with liver disease. This can affect patients' ability to do everyday tasks such as working, driving or managing their finances," Randolph, a clinical professor in the Department of Neurology at Loyola University Chicago Stritch School of Medicine.
Neurocognitive impairment in liver patients is called hepatic encephalopathy. It is believed to be caused by toxins such as ammonia that diseased livers do not clear from the body.
Randolph's study is the first to document how liver patients compare with the general population.
Liver patients from multiple centers nationwide were given a test developed by Randolph called the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).
The widely used paper-and-pencil test takes 20 to 25 minutes and measures memory, attention, language and visual-spatial functions. It includes tasks such as identifying line drawings of common objects, repeating lists of digits, copying geometrical figures and recalling a story.
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