Medindia

X

Lasers Used to Vaporize Tissue at Multiple Points Simultaneously

by Tanya Thomas on  September 16, 2011 at 9:38 PM Research News   - G J E 4
Researchers at Vanderbilt University have developed a new technique that uses a single UV laser pulse to zap away biological tissue at multiple points simultaneously, a method that could help scientists study the mechanical forces at work as organisms grow and change shape.
 Lasers Used to Vaporize Tissue at Multiple Points Simultaneously
Lasers Used to Vaporize Tissue at Multiple Points Simultaneously
Advertisement

UV lasers are a commonly-used tool for cutting into tissue, but the lasers usually make incisions by vaporizing one point at a time in a series of steps. If the initial laser pulse cuts into cells under tension, the tissue could spring back from the incision. This makes precise tasks, such as cutting around a single cell, difficult. The Vanderbilt team found a way around this problem by using a computer-controlled hologram to shape the phase profile of the UV pulse -basically applying a patterned delay onto different parts of the beam. When the pulse then passed through a lens, the altered phase profile yielded an interference pattern with bright spots at any user-desired pattern of points. Using this method, which can vaporize up to 30 points simultaneously, the researchers successfully isolated a single cell on a developing fruit fly embryo and then observed how the cell relaxed into a shape dictated solely by internal forces.

Advertisement
The technique, described in the September issue of the Optical Society's (OSA) open-access journal Biomedical Optics Express, could be applied to other model organisms, such as frogs or zebra fish.

Source: Eurekalert
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All